MUSM Clinical Faculty Development Series
Navigating the Polypharmacy Interactions of Clozapine: A Focus on CYP-450 Enzyme Subtypes and Corresponding Influencers
• Recognize—and anticipate—common side effects following clozapine administration
• Explain high-yield pharmacokinetic (CYP-450) considerations into clozapine dose adjustment decisions
• Weigh the risk vs life-saving benefits of clozapine in the treatment-resistant schizophrenic population
• Improve comfortability of clozapine administration and management, including dosage, titration, and dose-adjustments in various high-yield clinical cases